Phasic and Tonic Pain Differentially Impact the Interruptive Function of Pain

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Phasic and Tonic Pain Differentially Impact the Interruptive Function of Pain

The interruptive effect of painful experimental stimulation on cognitive processes is a well-known phenomenon. This study investigated the influence of pain duration on the negative effects of pain on cognition. Thirty-four healthy volunteers performed a rapid serial visual presentation task (RSVP) in which subjects had to detect (visual detection task) and count the occurrence of a target lett...

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Tonic pain attenuates phasic pain

Pain perception is closely related to the attentional level and the vigilance of the subject [4]. The intensity of a pain stimulus and its sensation do often not coincide. A common experimental example is the so-called pain-inhibiting-pain effect: A stressful stimulus, e.g. persistent or chronic pain, often elevates the threshold for brief pain stimuli applied during the same time. Stressful st...

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THE EFFECT OF LOCUS CERULEUS LESIONING ON TONIC AND PHASIC PAIN

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Analgesic effect of electrical stimulation and microinjection of L-glutamate into the paragigantocellularis nucleus on phasic and tonic pain

  The paragigantocellularis (PGi) nucleus constitutes a large portion of the ventral pontomedullary reticular formation. Neurons within the PGi have been implicated in a variety of functions including cardiovascular regulation, respiratory control, pain and analgesia. Investigators have demonstrated that electrical stimulation and microinjection of L-glutamate into the PGi produce antinocicepti...

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ژورنال

عنوان ژورنال: PLOS ONE

سال: 2015

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0118363